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Professional lip fillers come in many different formulations and can last for months or even years in some cases. These include hyaluronic acid, glycerin, collagen and silicone. Depending on the patient's needs, these can add volume to the lips or simply plump up existing tissue. In some cases, patients want a lighter alternative to surgical correction; these alternatives include Restylane and Juvéderm. When selecting a treatment option, doctors consider factors such as cost and side effects to provide their patients with the best options possible.